Publications

Sex-related external factors influence pulmonary vascular angiogenesis in a sex-dependent manner.

Hayward-Piatkovskyi B, Gonyea CR, Pyle SC, Lingappan K, Gleghorn JP

The Need to Address Sex as a Biological Variable in Neonatal Clinical Studies.

Lingappan K, Alur P, Eichenwald E

Lung biopsy in infants with severe bronchopulmonary dysplasia.

Callaway DA, Wang Y, Lingappan K, Pogoriler JE, Laje P, Nilan K, Kirpalani H, Zhang H

Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates.

Lingappan K, Neveln N, Arnold JL, Fernandes CJ, Pammi M

Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation.

Grimm SL, Stading RE, Robertson MJ, Gandhi T, Fu C, Jiang W, Xia G, Lingappan K, Coarfa C, Moorthy B

Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice.

Al-Mudares F, Cantu Gutierrez M, Cantu A, Jiang W, Wang L, Dong X, Moorthy B, Sajti E, Lingappan K

Endothelial to mesenchymal transition in neonatal hyperoxic lung injury: role of sex as a biological variable.

Cantu A, Cantu Gutierrez M, Zhang Y, Dong X, Lingappan K

Loss of microRNA-30a and sex-specific effects on the neonatal hyperoxic lung injury.

Grimm SL, Reddick S, Dong X, Leek C, Wang AX, Gutierrez MC, Hartig SM, Moorthy B, Coarfa C, Lingappan K

Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia.

Lingappan K, Olutoye OO 2nd, Cantu A, Cantu Gutierrez ME, Cortes-Santiago N, Hammond JD, Gilley J, Quintero JR, Li H, Polverino F, Gleghorn JP, Keswani SG

Modulation of Recovery from Neonatal Hyperoxic Lung Injury by Sex as a Biological Variable.

Cantu A, Gutierrez MC, Dong X, Leek C, Anguera M, Lingappan K

Pharmacotherapy of BPD: Current status & future perspectives.

Ryan RM, Mukherjee D, Ford S, Lingappan K

Toolkit for gender equity in pediatrics.

Machut KZ, Lingappan K, Savich R, Dammann CEL

"Exploring the Association of Male Sex with Adverse Outcomes in Severe Bronchopulmonary Dysplasia: A Retrospective, Multi-Center Cohort Study".

Hammond JD 2nd, Kielt MJ, Conroy S, Lingappan K, Austin ED, Eldredge LC, Truog WE, Abman SH, Nelin LD, Cuevas Guaman M

Remarkable sex-specific differences at Single-Cell Resolution in Neonatal Hyperoxic Lung Injury.

Cantu A, Gutierrez MC, Dong X, Leek C, Sajti E, Lingappan K

Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates.

Almudares F, Hagan J, Chen X, Devaraj S, Moorthy B, Lingappan K

Correction to: Call to action: gender equity in neonatology.

Machut KZ, Bhombal S, Escobedo M, Kataria-Hale J, Kushnir A, Lingappan K, Oji-Mmuo CN, Owens L, Savich R, Song C, Wright R, Dammann CEL

The Cellular and Molecular Effects of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia.

Olutoye Ii OO, Short WD, Gilley J, Hammond Ii JD, Belfort MA, Lee TC, King A, Espinoza J, Joyeux L, Lingappan K, Gleghorn JP, Keswani SG

Call to action: gender equity in neonatology.

Machut KZ, Bhombal S, Escobedo M, Kataria-Hale J, Kushnir A, Lingappan K, Oji-Mmuo CN, Owens L, Savich R, Song C, Wright R, Dammann CEL

Correction to: Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal β-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants.

Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI

Vision 2020: How Caregiving and Work Productivity Outlook Shifted for Academic Pediatric Faculty.

Chumpitazi CE, Camp EA, Cuevas-Guaman M, Doughty C, Kancherla B, Lingappan K, Moran NE, Murray KO, Perez O, Shekerdemian LS, O'Connor TM

Effect of Coronavirus Disease-2019 on the Workload of Neonatologists.

Machut KZ, Kushnir A, Oji-Mmuo CN, Kataria-Hale J, Lingappan K, Kwon S, Dammann CEL

National professional society augments career development and leadership amongst neonatal fellows and early career neonatologists.

Koo J, Lingappan K, Song C

Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells.

Burke R, Chu C, Zhou GD, Putluri V, Putluri N, Stading RE, Couroucli X, Lingappan K, Moorthy B

Effect of sex chromosomes versus hormones in neonatal lung injury.

Grimm SL, Dong X, Zhang Y, Carisey AF, Arnold AP, Moorthy B, Coarfa C, Lingappan K

Does the Epigenome Hold Clues to Leptin-associated Hypertension in Obesity?

Lingappan K

Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease.

Jain PN, Robertson M, Lasa JJ, Shekerdemian L, Guffey D, Zhang Y, Lingappan K, Checchia P, Coarfa C

The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury.

Stading R, Couroucli X, Lingappan K, Moorthy B

Role of Growth Differentiation Factor 15 in Lung Disease and Senescence: Potential Role Across the Lifespan.

Al-Mudares F, Reddick S, Ren J, Venkatesh A, Zhao C, Lingappan K

Molecular role of cytochrome P4501A enzymes inoxidative stress.

Stading R, Chu C, Couroucli X, Lingappan K, Moorthy B

Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic.

Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker CL, Moorthy B, Lingappan K

Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects.

Callaway DA, Jiang W, Wang L, Lingappan K, Moorthy B

Understanding the age divide in COVID-19: why are children overwhelmingly spared?

Lingappan K, Karmouty-Quintana H, Davies J, Akkanti B, Harting MT

The Wnt Signaling Pathway and the Development of Bronchopulmonary Dysplasia.

Lingappan K, Savani RC

Role of <i>HIF-1α-miR30a-Snai1</i> Axis in Neonatal Hyperoxic Lung Injury.

Zhang Y, Dong X, Lingappan K

Impact of Early Life Antibiotic Exposure and Neonatal Hyperoxia on the Murine Microbiome and Lung Injury.

Althouse MH, Stewart C, Jiang W, Moorthy B, Lingappan K

Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB).

Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou G, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B

MicroRNA-30a as a candidate underlying sex-specific differences in neonatal hyperoxic lung injury: implications for BPD.

Zhang Y, Coarfa C, Dong X, Jiang W, Hayward-Piatkovskyi B, Gleghorn JP, Lingappan K

Sex-specific differences in primary neonatal murine lung fibroblasts exposed to hyperoxia in vitro: implications for bronchopulmonary dysplasia.

Balaji S, Dong X, Li H, Zhang Y, Steen E, Lingappan K

Pulmonary endothelial cells exhibit sexual dimorphism in their response to hyperoxia.

Zhang Y, Dong X, Shirazi J, Gleghorn JP, Lingappan K

Mice Lacking the Cytochrome P450 1B1 Gene Are Less Susceptible to Hyperoxic Lung Injury Than Wild Type.

Veith AC, Bou Aram B, Jiang W, Wang L, Zhou G, Jefcoate CR, Couroucli XI, Lingappan K, Moorthy B

Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates.

Lingappan K, Arnold JL, Fernandes CJ, Pammi M

NF-κB in Oxidative Stress.

Lingappan K

Noninvasive ventilation strategies: which to choose?

Thomas AN, Hagan JL, Lingappan K

β-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type and Cyp1a2-knockout mice.

Lingappan K, Maturu P, Liang YW, Jiang W, Wang L, Moorthy B, Couroucli XI

Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice.

Jiang W, Maturu P, Liang YW, Wang L, Lingappan K, Couroucli X

Focused Evidence-Based Medicine Curriculum for Trainees in Neonatal-Perinatal Medicine.

Pammi M, Lingappan K, Carbajal MM, Suresh GK

Sexual dimorphism of the pulmonary transcriptome in neonatal hyperoxic lung injury: identification of angiogenesis as a key pathway.

Coarfa C, Zhang Y, Maity S, Perera DN, Jiang W, Wang L, Couroucli X, Moorthy B, Lingappan K

Sex-specific differences in the modulation of Growth Differentiation Factor 15 (GDF15) by hyperoxia in vivo and in vitro: Role of Hif-1α.

Zhang Y, Jiang W, Wang L, Lingappan K

Mind the gap: can videolaryngoscopy bridge the competency gap in neonatal endotracheal intubation among pediatric trainees? a randomized controlled study.

Parmekar S, Arnold JL, Anselmo C, Pammi M, Hagan J, Fernandes CJ, Lingappan K

Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome.

Lingappan K, Maity S, Jiang W, Wang L, Couroucli X, Veith A, Zhou G, Coarfa C, Moorthy B

Differential sex-specific effects of oxygen toxicity in human umbilical vein endothelial cells.

Zhang Y, Lingappan K

Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal β-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants.

Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI

One-Month-Old Infant With Hypotonia and Cardiorespiratory Arrest.

Hoover J, Lingappan K

Sex-specific differences in neonatal hyperoxic lung injury.

Lingappan K, Jiang W, Wang L, Moorthy B

Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury.

Dinu D, Chu C, Veith A, Lingappan K, Couroucli X, Jefcoate CR, Sheibani N, Moorthy B

Relationship between PCO2 and unfavorable outcome in infants with moderate-to-severe hypoxic ischemic encephalopathy.

Lingappan K, Kaiser JR, Srinivasan C, Gunn AJ

Can maternal DHA supplementation offer long-term protection against neonatal hyperoxic lung injury?

Lingappan K, Moorthy B

Role of GDF15 (growth and differentiation factor 15) in pulmonary oxygen toxicity.

Tiwari KK, Moorthy B, Lingappan K

Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.

Lingappan K, Jiang W, Wang L, Couroucli XI, Moorthy B

Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates.

Lingappan K, Arnold JL, Shaw TL, Fernandes CJ, Pammi M

Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.

Wang L, Lingappan K, Jiang W, Couroucli XI, Welty SE, Shivanna B, Barrios R, Wang G, Firoze Khan M, Gonzalez FJ, Jackson Roberts L, Moorthy B

Analysis of the transcriptome in hyperoxic lung injury and sex-specific alterations in gene expression.

Lingappan K, Srinivasan C, Jiang W, Wang L, Couroucli XI, Moorthy B

Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro.

Tiwari KK, Chu C, Couroucli X, Moorthy B, Lingappan K

Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress.

Lingappan K, Jiang W, Wang L, Wang G, Couroucli XI, Shivanna B, Welty SE, Barrios R, Khan MF, Nebert DW, Roberts LJ, Moorthy B

Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene.

Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI

Lactoferrin and the newborn: current perspectives.

Lingappan K, Arunachalam A, Pammi M

Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans.

Lingappan K, Jiang W, Wang L, Couroucli XI, Barrios R, Moorthy B

Whooping cough: the current scene.

Singh M, Lingappan K